LYCOS RETRIEVER 
Zyban: Nicotine
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Nicotine substitutes, such as nicotine patches or gum, work a little differently then Zyban. These substitutes provide nicotine to the bloodstream throughout the day. Medication such as Zyban works by providing a feeling of well-being to allow a smoker to give up their habit. It ... is effective for behavioural modifications.
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Researchers believe that Zyban interacts with the brain's neurotransmitters to reduce craving and the effects of withdrawal from nicotine addiction. The active ingredient, bupropion, is a relatively weak inhibitor of the neuronal uptake of dopamine, serotonin and norepinephrine. Zyban can be combined with nicotine replacement therapy like patches or gum.
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Clinical studies have ... shown Zyban works best in reducing withdrawal symptoms of nicotine, significant reduction in cigarette craving and elevated long term abstinence rate. Also, the ability to quit smoking with Zyban greatly depends on commitment.
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In 1997, the FDA approved Zyban to be used as a quit smoking aid, and since then, bupropion has become a popular method to help smokers kick the habit. Bupropion, when used in combination with other nicotine replacement therapies (NRT's), such as the nicotine patch or nicotine gum, increase the chances for long term success with smoking cessation.
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