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Zoloft: Studies
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Zoloft has not been shown to cause damage to the fetus during pregnancy, but it has not been fully studied in humans and proven safe. Animal studies did not indicate an increase of defects in offspring, but did show a slight increase in the death rate of newborn animals when Zoloft was taken in the last trimester of pregnancy, and a lower birth weight. Animal studies are not always predictive of results in humans.
* Special Considerations: In these trials, Zoloft was safe and well tolerated, with side effects similar to those seen in studies of Zoloft for other indications. Beneficial effects seen largely in women only
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No adverse events have been reported in babies exposed to Zoloft by breastfeeding. Where studied, developmental milestones have proceeded on course despite the fact that one baby was reported to have blood concentrations of Zoloft at half its mother's levels (Am J Psychiatry 1998 May;155(5):690-2).
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