LYCOS RETRIEVER 
Zanaflex
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Zanaflex® (tizanidine hydrochloride) is a centrally acting α2-adrenergic agonist. Tizanidine HCl (tizanidine) is a white to off-white, fine crystalline powder, which is odorless or with a faint characteristic odor. Tizanidine is slightly soluble in water and methanol; solubility in water decreases as the pH increases. Its chemical name is 5-chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiodiazole hydrochloride. Tizanidine's molecular formula is C9H8CIN5 S-HCl, its molecular weight is 290.2 and its structural formula is:
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Zanaflex is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain. Zanaflex is used to treat increased muscle tone associated with spasticity. Zanaflex may ... be used for purposes other than those listed in this medication guide.
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Before taking Zanaflex, tell your doctor if you have: any allergies, low blood pressure, liver or heart disease, kidney disease, eye disease. Limit the use of alcohol as alcohol may intensify the dizziness and drowsiness effects of Zanaflex. Use caution when driving or operating machinery or when alertness is required. Zanaflex should be used only when clearly needed during pregnancy. Discuss the risks and benefits of Zanaflex with your doctor. It is not known whether Zanaflex is excreted into human milk.
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Zanaflex can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Dizziness is most likely to occur when you rise from a sitting or lying position. Get up slowly to prevent dizziness and a possible fall. Do not use Zanaflex at a time when muscle tone is needed to assure safe balance and movement for certain activities. In some situations, it may endanger your physical safety to be in a state of reduced muscle tone.
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Zanaflex might cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, as well as fever can increase these effects. To halt them, sit up or stand slowly, especially in the morning. As well as, sit or lie down at the earliest sign of dizziness, lightheadedness, or weakness.
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Zanaflex may be taken with or without food. Zanaflex should be used only for short periods (no more than 3 weeks). Since the type of injury that Zanaflex treats should improve in a few weeks, there is no reason to use it for a longer period. Zanaflex may cause dry mouth. Sucking a hard candy, chewing gum, or melting ice chips in your mouth can provide temporary relief.
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