LYCOS RETRIEVER 
Vincristine: Injection
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Vincristine is for injection into a vein. It is usually given in a hospital or clinic setting by a trained health care professional. If you notice pain, swelling, burning or any unusual feeling around the site of your injection, tell your health care professional immediately. There may be several weeks between doses.
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The concentration of Vincristine Sulfate Injection is 1 mg/mL. Do not add extra fluid to the vial prior to removal of the dose. Withdraw the solution of Vincristine Sulfate Injection into an accurate dry syringe, measuring the dose carefully. Do not add extra fluid to the vial in an attempt to empty it completely.
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Vincristine is available in sterile vials or pre-filled syringes containing vincristine 1mg per 1mL of solution. Nonmedicinal ingredients include mannitol and water for injection. One of the two manufacturers of this product ... includes methylparaben and propylparaben as nonmedicinal ingredients.
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Vincristine sulfate injection should not be given to patients while they are receiving radiation therapy through ports that include the liver. When vincristine sulfate injection is used in combination with L-asparaginase, vincristine sulfate injection should be given 12 to 24 hours before administration of the enzyme in order to minimize toxicity; administering L-asparaginase before vincristine sulfate injection may reduce hepatic clearance of vincristine.
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