LYCOS RETRIEVER 
Trimethoprim: Bacteria
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Trimethoprim is an antibiotic that works in a similar way to a group of antibiotics called the sulphonamides. It works inside the bacterial cell, where it stops the manufacture of a chemical called folic acid. Folic acid is necessary for the production of genetic material (DNA). Without the production of DNA the bacteria is not able to reproduce, and the spread of the infection is stopped.
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Trimethoprim acts by interfering with the action of bacterial dihydrofolate reductase, inhibiting synthesis of tetrahydrofolic acid. Tetrahydrofolic acid is an essential precursor in the de novo synthesis of the DNA nucleosides thymidine and uridine. Bacteria are unable to take up folic acid from the environment (ie. the infection host) and are ... dependent on their own de novo synthesis. Inhibition of the enzyme starves the bacteria of two bases necessary for DNA replication and transcription.
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Trimethoprim alone is probably most commonly used for urinary tract infections (cystitis). It can be used both to treat a urinary tract infection and ... sometimes to help prevent them (e.g. in people who keep getting this type of infection). Trimethoprim may also be used for some other bacterial infections; in this case it is often combined with another antibiotic as co-trimoxazole. There are some bacteria that are not affected by trimethoprim (resistant).
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Trimethoprim, a antiinfective agent, is used to synthetic treat prevent urinary and tract diarrhea, infections, when combined with either. and, is Trimethoprim antibiotic. It fights an bacteria in body. Read your doctor-produced
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Trimethoprim belongs to the class of medications called antibiotics. It is used for the treatment of certain types of infections caused by bacteria. It is most commonly used to treat bladder (urinary tract) infections. Trimethoprim works by killing the bacteria that cause the infection.
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Trimethoprim works by preventing the bacteria from producing folate. Without folate, the bacteria cannot produce DNA and so are unable to increase in numbers. Trimethoprim therefore stops the spread of infection. The remaining bacteria are killed by the immune system or eventually die.
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