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Tetracycline
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Tetracycline is the most widely prescribed antibiotic for acne. The usual starting dose is 500 mg twice a day continued until a significant decrease in acne lesions is seen. The dose can then be decreased to 250 mg twice a day or discontinued. The main drawback for this antibiotic is that it must be taken on an empty stomach to be the most effective. For a teenage boy who eats frequently, this can be very difficult. Tetracycline should not be given to pregnant women or children under 9 years of age.
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Tetracycline antibiotics are the leading approved systemic treatments of moderate to severe inflammatory acne. Discovered decades ago as broad-spectrum systemic antibiotics, tetracyclines have been shown to be potent anti-acne agents. Paratek has utilized its expertise in chemistry to develop novel narrow-spectrum antibacterial tetracyclines with improved anti-inflammatory activity, tolerability and other properties for the next generation treatment of acne and rosacea. These compounds represent the first tetracycline-derived new molecular entities ever to be synthesized specifically as improved therapeutics for dermatologic diseases.
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Tetracycline antibiotics have a broad spectrum of activity, are relatively safe, can be used by many routes of administration, and are widely used. They even have antiprotozoal activity. The major difference among the tetracyclines is in their pharmacokinetic properties. Cross resistance among members of the group is frequent. On the other end of the spectrum, antibiotics are a poor choice for one who has been affected by fungal exposure; especially systemically. These should be avoided at all costs. There are substitutes on the market, both holistically and scientifically.
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Tetracycline can have toxic effects on development of bone. Therefore, tetracyclines are generally not recommended during pregnancy or nursing. Tetracyclines may cause discoloration of teeth if used in children less than 8 years of age.
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Tetracycline comes as a capsule and suspension (liquid) to take by mouth. It is usually taken two to four times daily. Tetracycline should be taken on an empty stomach, at least 1 hour before or 2 hours after meals or snacks. Drink a full glass of water with each dose of tetracycline. Do not take tetracycline with food, especially dairy products such as milk, yogurt, cheese, and ice cream. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
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Tetracycline comes in capsules, tablets, oral liquid, and injection form. Your prescription label tells you how much to take at each dose. Tetracycline should be taken on an empty stomach, one hour before or two hours after meals. The capsules and tablets should be taken with a full glass of water. Liquid tetracycline should be shaken well before each use to mix the medication evenly. You may obtain a specially marked measuring spoon from your pharmacist to be sure of an accurate dose.
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Tetracycline