LYCOS RETRIEVER 
Steroids: Taking
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Steroids are often injected directly into joints to treat conditions such as rheumatoid arthritis, gout or other inflammatory diseases. Steroids ... can be injected into inflamed bursae, or around tendons near the shoulder, elbow, hip, knee, hand or wrist.
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Steroids administered to previously untrained men beginning a weight training program appear to provide no benefit. It is only when highly trained individuals add a steroid regimen to their existing program that training gains are enhanced.
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The steroids are grouped together because their chemical structures are all very similar. The steroid chemical nucleus consists of four carbon rings, three 6-sided and one 5-sided, joined together by their edges. The specificity of their different biological actions is due to the various groups attached to a common nucleus. When alcohol groups (OH) are attached, steroids should properly be called sterols (such as cortisol), whereas ketone groups (C=O) make them sterones (such as aldosterone).
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[One] major class of lipids is steroids, which have structures totally different from the other classes of lipids. The main feature of steroids is the ring system of three cyclohexanes and one cyclopentane in a fused ring system as shown below. There are a variety of functional groups that may be attached. The main feature, as in all lipids, is the large number of carbon-hydrogens which make steroids non-polar.
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As part of Operation Gear Grinder, DEA ... identified over 2,000 U.S. customers that have received steroids from the businesses indicted today. These customers consist of individual users, street-level dealers, and organized trafficking groups in dozens of cities across the country.
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Current treatments for these diseases include steroids, methotrexate and various injectable biologic agents. Rigel's product candidate, R348, is believed to be orally bio-available and may provide an attractive alternative or supplement to currently used agents.
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