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Sarcoidosis: United States
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Sarcoidosis is a very puzzling disorder. In addition to having no clear-cut understanding of the cause of sarcoidosis, researchers are ... puzzled by its distribution in the world population. In the United States, for example, 10-17 times as many African-Americans are affected as white Americans. In Europe, whites are primarily affected.
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The skin is frequently affected by sarcoidosis. In Europeans, sarcoidosis often starts as raised, tender, red lumps, usually on the shins (erythema nodosum (see Itching and Noninfectious Rashes: Erythema Nodosum)), accompanied by a fever and joint pain, but this is less common in the United States. Prolonged sarcoidosis may lead to the formation of flat patches (plaques), raised patches, or lumps just under the skin with discoloration of the nose, cheeks, lips, and ears (lupus pernio). Lupus pernio is most common in black women.
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The limited data in this report indicate substantially higher sarcoidosis incidence rates for blacks than for whites enlisted in the USN and a clear decline in rates for blacks over time. The USN average annual sarcoidosis incidence rates per 100,000 for 1990-1993 (16.0 for black males and 2.5 for white males) were lower than average annual incidence rates for both black males (29.8) and white males (9.6) in a recently studied (1990-1994) population in Detroit, Michigan (2). However, reliable population-based rates over longer periods or for the United States are not available.
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Although sarcoidosis can occur in persons regardless of their race, gender or geographic location, it is more common among women and in African Americans. In the United States, the risk of sarcoidosis is up to twice as high in women compared to men, and three to four-fold greater in African Americans than in Caucasians.
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In the United States, a higher percentage of African Americans than whites has sarcoidosis, and the disease is usually more serious in them. The prevalence of sarcoidosis is eight times greater in African Americans than in whites in the U.S.
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You only need ONE positive biopsy to obtain a definitive diagnosis of sarcoidosis. If you have already had a biopsy, you do NOT need another. If your doctor is recommending a biopsy, please inform him/her that patients are recovering on the MP without the need of this invasive procedure that can have long-term consequences to the status of your lungs and yourbody will haveto heal the damage caused by the biopsy.
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