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Sarcoidosis: Acute Sarcoidosis
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Acute Sarcoidosis - about 75 percent of patients have the acute form of sarcoidosis. About half of these have no long term damage or significant problems. Sarcoidosis is often a mild condition with no permanent damage to the body's tissue.
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Because a number of lung diseases follow respiratory tract infections, ascertaining whether a virus can be implicated in the events leading to sarcoidosis remains an important area of research. Some recent observations seem to provide suggestive leads on this question. In these studies, the genes of cytomegalovirus (CMV), a common disease-causing virus, were introduced into lymphocytes, and the expression of the viral genes was studied. It was found that the viral genes were expressed both during acute infection of the cells and when the virus was not replicating in the cells. However, this expression seemed to take place only when the T-cells were activated by some injurious event.
Acute sarcoidosis is more common in whites than in blacks and usually is associated with spontaneous remission within two years. Spontaneous remission ... occurs in patients with Löfgren's syndrome, which consists of bilateral hilar lymphadenopathy, ankle arthritis, erythema nodosum, fever, myalgia, and weight loss.
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