LYCOS RETRIEVER 
Risperidone: Treatment
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Risperidone is an antipsychotic medication. It works by changing the effects of chemicals in the brain. It ... used for the treatment of schizophrenia and mania associated with bipolar disorder. It may be used for purposes other than those listed in this medication guide.
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Risperidone is a serotonin and dopamine receptor antagonist. It is approved for the treatment of schizophrenia, and is sometimes prescribed as an adjunct therapy for the treatment of aggression, Tourette's syndrome, bipolar disorder, obsessive-compulsive disorder and other disorders.
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Risperidone was approved earlier this year for treatment of irritability associated with autism. As part of that approval, the FDA requested long term follow-up studies and Dr. Laughren said the data from those post-marketing studies should elucidate the diabetes risk.
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Risperidone has not been evaluated or used to any appreciable extent in patients with a recent history of myocardial infarction or unstable heart disease. Patients with these diagnoses were excluded from clinical studies during the product's premarket testing. The electrocardiograms of approximately 380 patients who received Risperidone and 120 patients who received placebo in two double-blind, placebo- controlled trials were evaluated and the data revealed one finding of potential concern, i.e., 8 patients taking Risperidone whose baseline QTc interval was less than 450 msec were observed to have QTc intervals greater than 450 msec during treatment; no such prolongations were seen in the smaller placebo group. There were 3 such episodes in the approximately 125 patients who received haloperidol. Because of the risks of orthostatic hypotension and QT prolongation, caution should be observed in cardiac patients (See WARNINGS and PRECAUTIONS).
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Risperidone is used to treat severe mental illnesses such as schizophrenia and bipolar disease. It helps reduce symptoms such as hallucinations, delusions, and hostility. It is ... indicated for the treatment of irritability associated with autistic disorder.
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Risperidone is ... used for the short-term treatment of behavioural problems (such as verbal or physical aggression, suspiciousness, and agitation) in people with severe dementia. Medications like risperidone are thought to work by correcting the function of nerve pathways in certain areas of the brain.
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