LYCOS RETRIEVER 
Risperidone: Studies
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Risperidone can be beneficial in some features of autism. However there are limited data available from studies with small sample sizes. In addition, there lacks a single standardised outcome measure allowing adequate comparison of studies, and long-term followup is ... lacking. Further research is necessary to determine the efficacy pf risperidone in clinical practice.
Source:
Clinical studies of Risperidone did not include sufficient numbers of patients aged 65 and over to determine whether they respond differently from younger patients. In general, a lower starting dose is recommended for an elderly patient, reflecting a decreased pharmacokinetic clearance in the elderly, as well as a greater frequency of decreased hepatic, renal, or cardiac function, and a greater tendency to postural hypotension (See ACTIONS/CLINICAL PHARMACOLOGY and DOSAGE AND ADMINISTRATION).
Source:
Risperidone long-acting injection is marketed in the U.S. by Janssen, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc. The formulation is manufactured by Alkermes, Inc. (Nasdaq: ALKS). Ortho-McNeil Janssen Scientific Affairs, LLC, funded the study.
Source:
Risperidone is well absorbed, as illustrated by a mass balance study involving a single 1 mg oral dose of 14C-risperidone as a solution in three healthy male volunteers. Total recovery of radioactivity at one week was 85%, including 70% in the urine and 15% in the feces.
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