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Rhinitis: Sneezing
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The multi-center DARTT study was comprised of 738 subjects with ragweed allergic rhinitis, including 241 placebo subjects. A positive skin test to ragweed was required for enrollment in the study. On January 8, 2007, Dynavax reported that the placebo group overall did not demonstrate sufficient levels of ragweed allergic rhinitis and as a result, no meaningful clinical effect could be measured.
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Controversy surrounds nonallergic rhinitis because the epidemiology and diagnostic criteria are confusing. The main controversy is how to differentiate allergic rhinitis from nonallergic rhinitis. Furthermore, current research appears to delineate a third category that includes characteristics of both allergic and nonallergic rhinitis. Research shows that the prevalence of pure allergic rhinitis in the adult population with symptoms is 43 percent, combination allergic rhinitis and nonallergic rhinitis is 34 percent, and pure nonallergic rhinitis is 23 percent.
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Pregnancy rhinitis is actually one of the most common discomforts associated with pregnancy. Like morning sickness and backaches, thousands of pregnant women experience pregnancy rhinitis every year. In fact, it is believed that between 20% and 30% of all pregnant women will suffer from pregnancy rhinitis to some degree.
Different types of rhinitis are triggered by different factors. Before a diagnosis of allergic rhinitis is made, physicians must be sure another type of rhinitis is not to blame. Changes in the weather, hormones in the individual or physical defects in the nasal septum (partition in the nasal cavity) can all cause rhinitis symptoms.
The term "cobblestoning" is used to describe streaks of lymphoid tissue on the posterior pharynx, which is commonly observed with allergic rhinitis. Tonsillar hypertrophy can ... be observed. Malocclusion (overbite) and a high-arched palate can be observed in patients who breathe from their mouths excessively.
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Most rhinitis caused by a cold resolves completely in about a week. Complications are unusual but may include sinusitis (inflammation of the nasal sinuses), bacterial infections, or infections of the middle ear. Allergic rhinitis can usually be treated very effectively. Bacterial causes of rhinitis can usually be resolved fairly quickly with the use of antibiotics.
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