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Rheumatoid Arthritis: Drugs
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Spending on rheumatoid arthritis specialty medications overall is now higher than any other biotech category and has, for the first time, surpassed the cost of multiple sclerosis (MS) drugs. RA specialty medications have ... shown the largest increase in costs, making up 44 percent of the drug trend for the whole specialty category in 2004, more than double the increase for MS specialty drugs, the second highest trend group at 21 percent.
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Enbrel is indicated for "the reduction in signs and symptoms of moderately to severely active rheumatoid arthritis in patients who have an inadequate response to one or more disease-modifying anti-rheumatic drugs (DMARDs)". Enbrel can be used together with methotrexate in patients not responding to methotrexate alone. The dosage for adults is 25 mg. given two times a week as a subcutaneous injection.
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Methotrexate, a drug commonly prescribed to combat the effects of rheumatoid arthritis, is known to have toxic side effects. Folate is a recommended supplement to reduce the toxicity, allowing patients to continue their treatment for longer periods of time.
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