LYCOS RETRIEVER 
Remicade: Diseases
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[One] indication for Remicade is to help close intestinal fisulas. Common in Crohn's disease, a fistula is simply an abnormal "tunnel" that makes a path between two body cavities - such as between intestine and vagina, intestine and bladder, or from the intestine and through skin. One way a fistula may form is from an abscess - a pocket of pus in the body. The abscess may be constantly filling with body fluids such as stool or urine, which prevents healing. Eventually the fistula breaks through to the skin, another body cavity, or an organ. Fistulas are more common in Crohn's Disease than in ulcerative colitis.
Source:
The new Pharmacor report entitled Crohn's Disease finds that market growth through 2011 will be driven by the continued use of Centocor/Schering- Plough/Mitsubishi Tanabe's biologic agent Remicade, as well as by robust uptake of Abbott/Eisai's TNF-alpha inhibitor Humira. From 2011 through 2016, growth will be sustained by Humira and the launches of UCB/Nektar's Cimzia, Centocor/Janssen-Cilag's ustekinumab, Abbott's ABT-874, and Bristol-Myers Squibb's Orencia.
Source:
Research has shown that the majority of patients treated with Remicade achieved a 75% improvement or more in the psoriasis area and severity index, which measures the severity of psoriasis disease symptoms and impact on quality of life. An improvement of 50% is a clinically significant endpoint in the assessment of psoriasis.
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