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Quinine: Malaria
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Quinine is contraindicated in patients with a history of hypersensitivity and in the presence of haemoglobinuria during malaria and in patients with optic neuritis, or tinnitus (Reynolds, 1996). It should be used with caution in patients with atrial fibrillation and other myocardial conduction abnormalities. Quinine may enhance the effects of anticoagulants. In patients with myasthenia, quinine may cause severe respiratory distress and dysphagia. In patients with glucose-6-phosphate deficiency, blackwater fever may be observed when quinine is used (Reynolds, 1996).
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Quinine is generally used to treat patients with malaria. Quinine is harvested from the bark of cinchona trees in South America. Unfortunately, in recent years, Quinine has been used for "off-label" purposes to help patients with leg cramps. The off-label use has resulted in greater sales of the drug.
Quinine is a bitter tasting powder extracted from the bark of the cinchona tree of South America. Quinine, used in medicine, became popular as an antimalaria drug, and in the 1940's drug pushers, concerned about their decreasing clientele from the epidemic of malaria sweeping the streets, added quinine to heroin. As a result of this new practice, the malaria outbreak in New York was reasonably controlled. The use of quinine in illicit preparations continues today, because quinine's bitter taste prevents heroin buyers from being able to judge the quality of heroin sold as well as adds to the "rush" of the heroin injection.
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Quinine is a drug which is made from the bark of the Cinchona tree. A number of various other chemicals can ... be synthesised from Cinchona, and these include cinchonine, cinchonidine and quinidine. Even before the 1600s, the Peruvian Indians used an infusion of Cinchona bark to treat fever, and soon it was recognised that Cinchona bark was also effective at treating and preventing malaria. At that point of time, no one actually knew that the potent ingredient was the alkaloid quinine. It was not until 1820 (200 years after the bark was introduced into Europe for the treatment of malaria) that quinine was isolated from the bark of the Cinchona tree. Aside from the treatment of malaria, quinine has also been used as a flavouring, and it provides the bitter taste in tonic water.
Quinine is an alkaloid found in the bark of the cinchona tree. Quinine has been used to treat malaria (a recurring disease marked by severe chills and fever) since the early 1600s. It was the best chemotherapeutic (chemical therapeutic) agent available to combat the disease until the 1920s. Malaria treatment by quinine marked the first successful use of a chemical compound to treat an infectious disease.
Quinine is a drug that falls into the latter category, as it was first discovered by "Western" cultures in the 17th Century in South America. Originally, quinine was used to treat malaria, an extremely prevalent disease at the time. With the passage of time came new uses for quinine, but these new uses have led to serious problems. The quinine lawyers at Williams Kherkher have long understood the uses and risks involved with this substance and as a result of reports in recent years of serious side effects that arose from the use of this drug, our quinine attorneys have put together a source of information for you to use as you evaluate your situation.
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