LYCOS RETRIEVER 
Quinine: Malaria
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Quinine was the current treatment for malaria. Hahnemann discovered that if a healthy man took a diluted amount of quinine, he would have the same symptoms as if he had malaria. This was the beginning. The basic concept here is that the treatment for an illness is the same medication that can create the same symptoms. Likes cure likes. It's similar to the concept of immunology or vaccinations.
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Quinine is an alkaloid obtained from the bark of several species of the cinchona tree. Until the development of synthetic drugs, quinine was used as the primary treatment of malaria, a disease that kills over 100 million people a year. The cinchona tree is native to the eastern slopes of the Andes Mountains in South America. Today, the tree is cultivated throughout Central and South America, Indonesia, India, and some areas in Africa. The cinchona tree contains more than 20 alkaloids of which quinine and quinidine are the most important. Quinidine is used to treat cardiac arrhythmias.
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Quinine sulfate (Formula Q) -- Used for malaria treatment only, has no role in prophylaxis. Use with second agent in drug-resistant P falciparum. For drug-resistant parasites, second agent is doxycycline, tetracycline, pyrimethamine sulfadoxine, or clindamycin. Quinidine gluconate is an IV alternative. Can ... be administered by deep IM injection.
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Quinine has many uses and applications. Some of the more common uses include: Analgesic, Anaesthetic, Antibacterial, Anti-malarial, Anti-microbial, Anti-parasitic, Antiseptic, Astringent, Febrifuge, Muscle-relaxant Other applications include: Bactericide, Contraceptive, Insecticide, Insect-repellent, Stomachic, Tonic
Quinine stimulates insulin secretion and in therapeutic doses it can cause hypoglycemia. This can be more severe in patients with severe infection and in pregnancy. Hypoglycemia in malaria may go unnoticed and could even cause death. Therefore, it is advisable to monitor blood glucose levels at least once in 4-6 hours while quinine is administered, especially in severe infection and in pregnancy. Quinine induced hypoglycemia can recur even after administration of 25% or 50% dextrose. In such situations, maintenance with a 10% dextrose infusion is advisable.
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Quinine, an alkaloid derived from the bark of the cinchona tree, has long been used for medicinal purposes. In the 19 th century, quinine gained popularity as an effective treatment for malaria. However, it is now ... being used for the treatment/prevention of leg cramps and other conditions, despite the fact that the Food and Drug Administration has deemed the drug ineffective and inappropriate for these uses. According to FDA, use of quinine products for treating conditions other than malaria are not justified because of the serious risks associated with their use.
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