LYCOS RETRIEVER 
Quinine: Drugs
built 648 days ago
Adverse effects: Quinine is a potentially toxic drug. The typical syndrome of quinine side effects is called as cinchonism and it can be mild in usual therapeutic dosage or could be severe in larger doses. Mild cinchonism consists of ringing in the ears, headache, nausea and disturbed vision. Functional impairment of the eighth nerve results in tinnitus, decreased auditory acuity and vertigo. Visual symptoms consist of blurred vision, disturbed colour perception, photophobia, diplopia, night blindness, and rarely, even blindness. These changes are due to direct neurotoxicity, although vascular changes may contribute to the problem.
Source:
Quinine can cause thrombocytopenia which may be fatal. There have been reports of haemolytic uraemic syndrome with acute renal failure following a single dose of quinine 300mg. Acute haemolytic anaemia is rare and normally disappears on withdrawal of the drug.
Source:
Quinine poses serious and potentially deadly risks. These side effects clearly outweigh the potential benefits of using this drug for the treatment or prevention of nocturnal leg cramps. Quinine adverse reactions include:
Source:
Quinine, it's stereoscopic isomer quinidine and their metabolites are detected in urine by Thin Layer Chromatography (TLC). Urine extracts are spotted onto a TLC plate and developed in a solvent. Quinine is distinguished by three spots for the free drug as well as two metabolites. Each of these spots will give off a bright fluorescent color when exposed to ultraviolet light. Quinine/quinidine will ... respond to the standard iodoplatinate reagent used to detect most alkaloidal drugs. The fact that there are three distinctive spots means that the identification of quinine is very specific and reliable.
Source:
Medications other than those listed above may interact with Quinine. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Source:
MORE ABOUT
Drugs