LYCOS RETRIEVER 
Propoxyphene: Propoxyphene Hydrochloride
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Propoxyphene is a centrally acting narcotic analgesic agent. Equimolar doses of propoxyphene hydrochloride or napsylate provide similar plasma concentrations. Following administration of 65, 130, or 195 mg of propoxyphene hydrochloride, the bioavailability of propoxyphene is equivalent to that of 100, 200, or 300 mg respectively of propoxyphene napsylate. Peak plasma concentrations of propoxyphene are reached in 2 to 2 1/2 hours. After a 100-mg oral dose of propoxyphene napsylate, peak plasma levels of 0.05 to 0.1 mcgm/mL are achieved.
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Darvon ® (Propoxyphene Hydrochloride, USP) is an odorless, white crystalline powder with a bitter taste. It is freely soluble in water. Chemically, it is (2S,3R)-(+)-4-(Dimethylamino)-3-methyl-1,2-diphenyl-2-butanol propionate (ester) hydrochloride, which can be represented by the accompanying structural formula. Its molecular weight is 375.94.
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Darvocet is a brand name for mild narcotic analgesic drug which combines Acetaminophen and Propoxy or Propoxyphene, prescribed for the relief of mild to moderate pain, with or without fever. It is sold as: Darvocet A500, Darvocet N 100, Darvocet N 50, Propacet 100, Wygesic, Darvon-N (propoxyphene napsylate), Darvon (propoxyphene hydrochloride), Darvon Compound-65 (propoxyphene hydrochloride, aspirin, and caffeine
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Propoxyphene Hydrochloride