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Primary Pulmonary Hypertension: Pulmonary Arteries
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While the specific cause of Primary Pulmonary Hypertension is not known, there are a variety of causes which have been found to contribute to Primary Pulmonary Hypertension. One of these is the appetite suppressant known as Fen-Phen, which has been shown to constrict or narrow the pulmonary artery.
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Primary pulmonary hypertension (PPH) is a rare disease characterized by elevated pulmonary artery pressure with no apparent cause. PPH is ... termed precapillary pulmonary hypertension or, more recently, idiopathic pulmonary arterial hypertension (IPAH). The diagnosis is usually made after excluding other known causes of pulmonary hypertension. Dresdale and colleagues first reported a hemodynamic account of IPAH in 1951. For additional resources, please visit Pulmonary Arterial Hypertension.
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Pulmonary hypertension often presents with nonspecific symptoms (Table 4). These symptoms are often difficult to dissociate from those caused by a known underlying pulmonary or cardiac disorder. The most common symptoms--exertional dyspnea, fatigue and syncope--reflect an inability to increase cardiac output during activity. Typical angina may occur despite normal coronary arteries. The mechanism is unclear, but anginal chest pain may be due to pulmonary artery stretching or right ventricular ischemia.
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The term primary pulmonary hypertension (PPH) has now been replaced with idiopathic pulmonary arterial hypertension (IPAH) in much of the medical literature. However, some physicians continue to use the older classification inappropriately.
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Pulmonary Arteries