LYCOS RETRIEVER 
Primary Pulmonary Hypertension: Drugs
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There is evidence that primary pulmonary hypertension can develop following the use of certain diet drugs that have been banned by the FDA. An experienced attorney can help you fight for justice and obtain valuable reparations that can offset medical expenses and create a more stable future. Do not hesitate to discuss your case with an understanding lawyer today.
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Clapham lives in San Diego and has Flolan, a drug used to treat primary pulmonary hypertension, injected into him all hours of the day. Pulmonary hypertension is what is holding him back from being placed on the wait list. However, once he receives a transplant, he will no longer need to use Flolan.
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A recent surge in diagnosed cases of primary pulmonary hypertension would echoearlier findings by French doctors on a nearly identical diet drug called Aminorex used in Europe during the 1960s. That study outlined a roughly 4-to-6-year interval between Aminorex use and the onset of an epidemic in cases of PPH, which continued into the 1970s, years after the European authorities pulled Aminorex from the market.
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Only up to 25% of patients with PPH demonstrate significant pulmonary vasoreactivity. If patients demonstrate vasoreactivity and are candidates for high-dose CCB therapy, administer a CCB challenge to stable patients to determine the vasodilator response. Perform this in the critical care unit with a balloon flotation catheter in the pulmonary artery. Administer oral nifedipine every hour (diltiazem can be used if resting tachycardia is present) until a 20% decrease in pulmonary artery pressure and pulmonary vascular resistance is observed or systemic hypotension or other adverse effects preclude further drug administration.
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