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Primary Pulmonary Hypertension: Diseases
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In familial cases, primary pulmonary hypertension is transmitted as an autosomal dominant trait if it occurs in several generations of the same family. Genetic diseases are determined by two genes, one received from the father and one from the mother. Dominant genetic disorders occur when only a single copy of an abnormal gene is necessary for the appearance of the disease. The abnormal gene can be inherited from either parent, or can be the result of a new mutation (gene change) in the affected individual. The risk of passing the abnormal gene from affected parent to offspring is 50% for each pregnancy regardless of the sex of the resulting child.
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Primary Pulmonary Hypertension (PPH) is a dangerous disease that causes an increased pulmonary artery pressure that has been found to occur in Fen Phen, Redux, and Pondimin users. A study published in the New England Journal of Medicine back in 1996 found a twenty-three-
PPH Patient Handouts Primary Pulmonary Hypertension (PPH) has no known cure. However, one does not have to live in discomfort and a fear of the disease consuming them. Medications and treatments are available to help ease the unpleasant symptoms and slow down the progression of the disease. Although some do not see the purpose of a medicine without a cure, many people give thanks that they are able to continue their lives in an orderly manner.
Primary pulmonary hypertension is an unusually aggressive and often fatal form of pulmonary hypertension that commonly affects young people. Whereas it is known that the arterial obstruction is caused by a building up of the smooth muscle cells that line the arteries, the underlying cause of the disease has long been a mystery.
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November is Pulmonary Hypertension Awareness month. This year marks the ten-year anniversary of a national initiative to create awareness for what once was an obscure illness. Today millions of dollars are committed to the search for a cure. Although Renie lived a little over three years after her diagnosis, today there are cases of those living twenty years and beyond. With the heightened involvement of the public to combat this disease, there is hope and encouragement for those living with PPH today!
The exact cause of primary pulmonary hypertension is unknown. In approximately 6-10 percent of cases (familial cases), a genetic predisposition to this disorder has been observed. A genetic predisposition means that a person may carry a gene for a disease, but the gene may not be expressed unless something in the environment triggers the disease process.
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