LYCOS RETRIEVER 
Prednisone
built 631 days ago
Prednisone is an oral, synthetic (man-made) corticosteroid used for suppressing the immune system as well as inflammation. It has effects similar to other corticosteroids such as triamcinolone (Kenacort), methylprednisolone (Medrol), prednisolone (Prelone) as well as dexamethasone (Decadron). These synthetic corticosteroids mimic the action of cortisol (hydrocortisone), the naturally-occurring corticosteroid produced in the body by the adrenal glands. Corticosteroids possess many effects on the body, but they most often are used for their potent anti-inflammatory effects, particularly in those conditions in which the immune system plays an substantial role. Such conditions include arthritis, colitis, asthma, bronchitis, confident skin rashes, as well as allergic or inflammatory conditions of the nose as well as eyes. Prednisone is inactive in the body as well as, in order to be effective, earliest must be converted to prednisolone by enzymes in the liver.
Source:
Prednisone is a very strong medication, and MUST be administered under a physician's prescription and close surveillance. Treatment should start with several tests to provide a baseline from which to measure the results. Treatment with prednisone is not a stand-alone intervention for autism. Parents MUST ... pursue appropriate interventions such as behavioral therapy, speech and occupational therapy where needed, and should not rule out dietary interventions. Other medications may be called for as well (e.g., Prozac, Clonidine), though the neurologist may wait to use other medications until treatment with prednisone is finished, or may recommend continuing with medications already in use.
Source:
Prednisone has a wide range of uses. In children, it is most commonly prescribed to treat asthma attacks, allergic reactions, poison ivy, arthritis (JRA), acute leukemia, congenital adrenal hyperplasia, adrenocortical insufficiency, and nephrotic syndrome. It is ... indicated for a variety of other endocrine, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, gastrointestinal, and nervous system disorders.
Source:
The amount of Prednisone prescribed for you depends on the severity of your skin problem. The starting dose is an estimate; it may have to be increased or decreased, depending on your response to it. Prompt improvement is important not just to clear your skin, but ... to hold down the severity of side effects. As your skin improves, the dose of prednisone will gradually be decreased. When your skin has cleared, or nearly so, the Prednisone tablets will be stopped. If you've been taking Prednisone for only one or two weeks, it's safe to stop taking it all at once.
Source:
Prednisone may cause acne of the face, chest, and back - "steroid acne." This is especially a problem in teenagers, but can occur at any age. In most cases, keeping the skin as clean as possible and using topical antiacne medications will control the problem. If simple measures don't help, a consultation with a dermatologist may be needed. Patients on prednisone ... often notice that they bruise easily, even with only slight trauma. Other skin problems include slow wound healing, redness of the face (plethora), stretch marks, night sweats, and increased facial hair.
Source:
Prednisone is readily absorbed from the gastro-intestinal tract and has a preconversion biological half-life of about 60 minutes before hydroxylation in the liver to its active metabolite prednisolone. Prednisolone has a plasma half-life of 2 to 3 hours and is extensively bound to plasma proteins. There are wide inter-individual differences in the rate of metabolism of prednisolone. Prednisolone is metabolised primarily in the liver to biologically inactive metabolites (primarily the gluconoride and sulphate). Prednisone is excreted in the urine as free and conjugated metabolites together with an appreciable amount of unchanged prednisolone. The conversion of prednisone is probably not diminished by liver disease.
Source:
MORE ABOUT
Prednisone