LYCOS RETRIEVER 
Nortriptyline
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Nortriptyline should not be given to children under 12 years old. Nortriptyline should only be given to adolescents under 18 who are under the care of a child psychiatrist. For adolescents 12-18 a reduced dosage may be needed.
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Children and teenagers who take Nortriptyline may be at increased risk for suicidal thoughts or actions. Adults may ... be affected. The risk may be greater in patients who have had suicidal thoughts or actions in the past. The risk may also be greater in patients who have had bipolar (manic-depressive) illness, or if their family members have had it.
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Nortriptyline is metabolised in the liver by hepatic enzyme CYP2D6. Approximately 7 to 10 percent of caucasians are poor metabolisers and might experience more adverse effects, so a lower dosage is often necessary in these individuals.
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Nortriptyline, the N-demethylated metabolite of amitriptyline, is as effective as imipramine in the treatment of depressive episodes of major depression and bipolar disorder. It may ... be useful in dysthymic disorder and atypical depression.
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Nortriptyline can interact with many other medicines. Some interactions can be very important. Make sure your prescriber or health care professional knows about all other medicines you are taking. Many important interactions are listed below:
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Nortriptyline must be taken regularly to be effective and it may be several weeks before you begin to feel better. Do not skip doses, even if they seem to make no difference.
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Nortriptyline