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Nortriptyline: Medications
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Nortriptyline is a tricyclic antidepressant of the dibenzocycloheptene type and is the active metabolite of amitriptyline. Nortriptyline is similar to protriptyline. Medications in this class are often referred to as tricyclic antidepressants, or TCAs. Depression is an all-pervasive sense of sadness and gloom. In some patients with depression, abnormal levels of brain neurotransmitters (chemicals that the nerve cells use to communicate with each other) may be responsible for the depression. Nortriptyline elevates the mood ("anti-depresses") by raising the level of neurotransmitters in brain tissue.
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Nortriptyline is available with a prescription under the brand name Pamelor. Other brand or generic formulations may ... be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.
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Nortriptyline is considered as having a risk of causing torsade de pointes. The risk of drug-induced torsade de pointes is extremely low when a single QT interval prolonging drug is prescribed. It is not known what effect vasoconstrictors in the local anesthetic regimen will have in patients with a known history of congenital prolonged QT interval or in patients taking any medication that prolongs the QT interval. Until more information is obtained, it is suggested that the clinician consult with the physician prior to the use of a vasoconstrictor in suspected patients, and that the vasoconstrictor (epinephrine, levonordefrin [Neo-Cobefrin®]) be used with caution.
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Nortriptyline is used to treat depression. Nortriptyline is in a group of medications called tricyclic antidepressants. It works by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance.
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Nortriptyline will add to the effects of alcohol and other central nervous system depressants (e.g., antihistamines, sedatives, tranquilizers, prescription pain medications, seizure medications, muscle relaxants, sleeping medications), possibly causing drowsiness. Be sure that your physician knows if you are taking these or any other medications.
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