LYCOS RETRIEVER 
Niaspan: Drugs
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Flushing occurs with Niaspan Controlled-Release Tablets and may last for several hours. Talk with your doctor if flushing becomes bothersome. Take Niaspan Controlled-Release Tablets at bedtime so that flushing will occur during sleep. If you are awakened by flushing at night, get up slowly, especially if you feel dizzy or faint or if you are taking blood thinners. Take aspirin or a nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen) 30 minutes before taking Niaspan Controlled-Release Tablets to lessen flushing.
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SIMCOR combines two well-established and leading medications, Niaspan and simvastatin, to target multiple lipid parameters – LDL, HDL and triglycerides – in a single pill. Abbott submitted its New Drug Application to the Food and Drug Administration for SIMCOR in April 2007. The submission includes data from the Phase III pivotal SEACOAST trial.
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In a related move, CMS instructed call centers fielding questions about Part D to tell inquirers that AARP and Humana prescription drug plans had "mistakenly" included Niaspan on their formularies. According to a footnote in the call centers' scripts, CMS had told those plans to remove Niaspan from their formularies.
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The cholesterol-lowering drugs known as bile acid sequestrants can cancel Niaspan's effect when taken at the same time. Try to space doses of the two types of drug at least 4 to 6 hours apart.
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