LYCOS RETRIEVER 
Niacin: Niacin Flush
built 639 days ago
The niacin used in Schiff Flush Free Niacin is Inositol Hexanicotinate, a different kind of time-release niacin. Inositol hexanicotinate is absorbed by the body, and inside of tissues, enzymes normally present in all cells slowly release niacin from the inositol. This allows niacin from inositol hexanicotinate to avoid flushing and provide what the cells really want - niacin in the right place at the right time in the right amounts. Niacinamide, another form of Vitamin B3 commonly used in dietary supplements and found in foods, does not cause flushing at any dose, but ... does not have the cardiovascular health effects that niacin has. Niacin is involved in numerous reactions inside of cells that convert food into cellular energy. Niacin helps operate enzymes that transport and break down fats, carbohydrates, proteins and other molecules formed from food.
Source:
Niacin is a form of vitamin B3, one of the water soluble B complex vitamins. Vitamin B3 is needed by the body to convert fats, carbohydrates, and proteins into energy. Niacin has been shown to dramatically lower blood cholesterol (LDL - the bad cholesterol) and triglyceride levels, while at the same time increasing HDL levels (the good cholesterol). For these reasons, niacin can reduce the risk of heart attacks and possible reverse atherosclerosis. Niacin ... appears to help against some forms of arthritis and migraines. Niacin expands (dilates) blood capillaries, which leads to the "niacin flush", an itching and reddening sensation that some people experience with high doses of niacin.
Source:
Vitamin B3 (Niacin) is necessary for proper circulation, healthy skin, and is important for the proper functioning of the nervous system. It is involved in the normal formation of stomach fluids and secretion of bile, along with the synthesis of the sex hormones. It dilates the blood vessels and brings blood to the surface of the skin. It lowers triglycerides, cholesterol and is considered helpful for schizophrenia and other mental illnesses. Note: A "flush" may occur after taking niacin. It is harmless, diminishes after 30 minutes or so, and can be reduced by taking niacin with a meal and an extra glass of water. If you are taking 2 tablets of Hair Formula 37 Step One at a time try taking one with a meal and another with another meal to reduce the flushing effect (if you want it to stop).
Source:
Niacinamide, another form of Vitamin B3 commonly used in dietary supplements and found in foods, does not cause flushing at any dose, but ... does not have the cardiovascular health effects that niacin has. Niacin is involved in numerous reactions inside of cells that convert food into cellular energy. Niacin helps operate enzymes that transport and break down fats, carbohydrates, proteins and other molecules formed from food. A normal function of niacin is to help remove fats (triglycerides) from tissues and the bloodstream.
Source:
Niacin is well established as a medical treatment for hyperlipidemia (3) and available by prescription in 50-mg to 500-mg tablets or capsules. The initial recommended therapeutic daily dose is 100 mg, three times a day, titrated to a maximum daily dose of 1,000 mg (4). Extended-release niacin tablets and capsules (at 125 mg--1,000 mg) ... are available by prescription, usually in a dose of 500 mg at bedtime, to a maximum of 2,000 mg per day. The therapeutic use of niacin often is limited by dermatologic and gastrointestinal ADRs (e.g., tachycardia, flushing, rash, nausea, vomiting, or abdominal pain). These effects usually are self-limited and are more common with dosages >1,000 mg per day, but can occur at any dose. Hepatotoxicity is a rare but serious adverse effect, usually associated with chronic use (5).
Source:
Niacin is used in the treatment of hyperlipidemia because it reduces VLDL secretion from the liver and inhibits cholesterol synthesis. There are two ways to reduce cholesterol levels, either by reducing dietary intake of cholesterol, or by decreasing cholesterol synthesis, for example with Niacin supplementation. Since VLDL is a precursor of LDL (bad cholesterol), LDL levels decrease with Niacin treatment. The main side effect is cutaneous flushing. [Katzung and Trevors Pharmacology Examination and Board Review 7th edition, Authors: Trevor, Anthony J. Katzung, Bertram G. and Masters, Susan B., Lange Medical Books/ McGraw-Hill 2005]
Source:
MORE ABOUT
Niacin Flush