LYCOS RETRIEVER 
Niacin: Blood
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Niacin taken in high doses is known to cause a wide range of adverse effects. The RDA for niacin is 20 milligrams. Niacin is marketed in dietary supplements at potencies of 250 mg, 400 mg, and 500 mg, in both immediate and slow-release formulations. Daily doses of 500 mg from slow-release formulations, and 750 mg of immediate-release niacin, have been associated with severe adverse reactions, including gastrointestinal distress (burning pain, nausea, vomiting, bloating, cramping, and diarrhea) and mild to severe liver damage. Less common, but more serious (in some cases life-threatening), reactions include liver injury, myopathy (muscle disease), maculopathy of the eyes (injury to the eyes resulting in decreased vision), coagulopathy (increased bleeding problems), cytopenia (decreases in cell types in the blood), hypotensive myocardial ischemia (heart injury caused by too low blood pressure), and metabolic acidosis (increases in the acidity of the blood and urine).
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Niacin, when taken in large doses, blocks the breakdown of fats in adipose tissue... altering blood lipid levels. Niacin is used in the treatment of hyperlipidemia because it reduces very-low-density lipoprotein (VLDL), a precursor of low-density lipoprotein (LDL) or "bad" cholesterol. Because niacin blocks breakdown of fats, it causes a decrease in free fatty acids in the blood and, as a consequence, decreased secretion of VLDL and cholesterol by the liver.[7]
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Niacin is used with diet changes to minimize the amount of cholesterol & some fatty substances in your blood. It is ... used to used to prevent & treat in cases of pellagra (niacin deficiency), a disease caused by inadequate diet and other medical issues.
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Having played straightforward hard rock with Mr. Big since the tail end of the '80s, bass virtuoso Billy Sheehan formed Niacin as an outlet for his jazz fusion and prog rock inclinations during the mid-'90s. The trio ... featured keyboardist John Novello and drummer Dennis Chambers, both musicians who had crossed frequently between the worlds of jazz and rock during their careers. With Niacin, Novello devoted himself especially to the Hammond B-3 organ, a longtime mainstay of both jazz and prog rock. The band recorded a self-titled debut album in 1996, following it up in 1998 with High Bias. An import-only concert recording, Live!: Blood, Sweat and Beers, surfaced later that year as well. For their next album, Niacin moved from Stretch to Magna Carta, the label that became virtually synonymous with technique-oriented neo-prog rock at the turn of the millennium.
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Niacin is beneficial for reducing high blood pressure and cholesterol levels, assisting insulin in the regulation of blood sugar levels and improving circulation. In addition, Niacin may be used to help alleviate depression, relieve insomnia and reduce hyperactivity.
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Taking a B-Complex along with Niacin will make its effect better. Some of the important improvements in the health as a result of taking Niacin are: helps counteract arteriosclerosis (hardening of the arteries), helps reduce cholesterol, helps increase circulation, helps reduce high blood pressure, helps reduce migraine headaches and helps reduce confusion.
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