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Naproxen: Naproxen Sodium
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Naproxen sodium is a non-steroidal anti-inflammatory drug (NSAID) and is contained in Anaprox®, Anaprox DS®, Naprelan®, Aleve® and in a number of over-the-counter medications. Naproxen sodium is indicated for the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and juvenile arthritis. It is ... indicated for the treatment of tendonitis, bursitis, acute gout and for the management of pain and primary dysmenorrhea. Naproxen-containing products should not be used by patients who have had allergic reactions to any product containing naproxen, nor in patients in whom aspirin or other NSAIDs induce the syndrome of asthma, rhinitis, and nasal polyps. Patients who have a history of peptic ulcer or gastrointestinal bleeding, kidney problems, uncontrolled hypertension or heart failure should consult a physician before using naproxen-containing medications. NSAIDs may cause increased risk of serious cardiovascular thrombotic events, myocardial infarction and stroke.
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Naproxen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and swelling (inflammation). Naproxen Sodium is ... used to treat headaches, muscle aches, backaches, tendonitis, bursitis, dental pain, menstrual cramps, arthritis, or gout. Naproxen Sodium may be used to treat other conditions as determined by your doctor. Naproxen Sodium works by blocking the enzyme in your body that makes prostaglandins. Decreasing prostaglandins helps to reduce pain and swelling.
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Naproxen and naproxen sodium have the potential to interfere with the antiplatelet effect of low-dose aspirin. One study of naproxen and low-dose aspirin has suggested that naproxen may interfere with aspirin's antiplatelet activity when they are coadministered (Steinhubl, 2005). However, naproxen 500 mg administered 2 hours before or after aspirin 100 mg did not interfere with aspirin's antiplatelet effect. The FDA stated that there is no data looking at doses of naproxen <500 mg. Naproxen over-the-counter strength is 220 mg tablets.
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Naproxen tablets, USP are available as yellow tablets containing 250 mg of Naproxen, orange tablets containing 375 mg of Naproxen and yellow tablets containing 500 mg of Naproxen for oral administration. The inactive ingredients are croscarmellose sodium, FD & C Yellow #6 aluminum lake, magnesium stearate, and povidone. The 250 mg and 500 mg ... contain D &C Yellow #10 aluminum lake.
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Naproxen was first and originally marketed as the prescription drug Naprosyn in 1976 and naproxen sodium was first marketed under the trade name Anaprox in 1980. It remains a prescription-only drug in much of the world. The U.S. Food and Drug Administration (FDA) approved the use of naproxen sodium as an over-the-counter (OTC) drug in 1994, where OTC preparations are sold under the trade name Aleve. In Australia, small packets of lower-strength preparations of naproxen sodium are Schedule 2 Pharmacy Medicines.
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Naproxen has been used for more than 30 years in the United States as a prescription product. Since its introduction as an OTC product in June 1994, ALEVE(R) (naproxen sodium) has been used by millions of Americans as a safe and effective pain reliever for more than a decade. With the convenience of all day relief with just two pills, ALEVE can be used for the treatment of aches and pains due to minor arthritis pain, muscle aches, backache, headache, toothache, menstrual pain and pain associated with the common cold.
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Naproxen Sodium