LYCOS RETRIEVER 
Metronidazole: Bacteria
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MECHANISM OF ACTION — Metronidazole is cytotoxic to facultative anaerobic bacteria, such as Helicobacter pylori and Gardnerella vaginalis, but the mechanism of this action is not well understood [1]. However, its activity against obligate anaerobes occurs through a four-step process:
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Lamont has argued that Metronidazole is not the right antibiotic to administer in these circumstances and was often administered too late to be of use. Clindamycin administered early in the second trimester to women who test positive for bacterial vaginosis seems to be more effective.[3]
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