LYCOS RETRIEVER 
Mesothelioma Clinical Trial: Cancer
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Researchers conduct clinical trials in many different settings. Major cancer centers are the most common; because they usually have the most advanced facilities and highly trained staffs, they can conduct all phases of clinical trials. But they are not the only places where these studies take place.
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The physician who diagnosed your mesothelioma may be able to refer you to an appropriate mesothelioma clinical trial. You can ... check the websites of the U.S. National Institutes of Health (NIH) and the National Cancer Institute (NCI); each has a registry of clinical trials for cancer treatments.
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A good place to start is the National Cancer Institute's clinical trials search form, where you'll find many trials for mesothelioma and other types of cancer. You may ... want to visit one of the commercial trial-finder sites listed below. There you will find NCI-sponsored and pharmaceutical company-sponsored clinical trials.
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Most people don't pay much attention to clinical trials until they are diagnosed with a serious illness such as cancer. You may have seen stories in the news about something going wrong in a clinical trial. The media is quick to pick up on an instance when a volunteer in a study is harmed. While it is very rare, people have been harmed, and have even died, while taking part in clinical trials. This is even more tragic when it could have been prevented. Reports of these tragic outcomes are important, because they help to expose problems in the system, which are then corrected to protect others.
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Researchers review clinical trials targeting lung cancer with vaccine immunotherapy in a recent issue of Expert Review of Anticancer Therapy. According to the review from the United States, "Successful active immunotherapy is expected to be specific and nontoxic. Until now, the success of immunotherapy in cancer has been sporadic and unpredictable. This has been attributable in part to the lack of a full understanding of the mechanistic underpinnings of immune regulation." "Furthermore, the lack of systematic success of immunotherapy, as argued in this review, stems from failing to effectively target tumors such as non-small cell lung cancer," said Luis E. Raez and collaborators at the University of Miami and Tulane University.
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When clinical trials do look at drugs, not all of them study new ones. Even after a drug has been approved for use against a type of cancer, doctors sometimes find it works better when given a certain way or when combined with other treatments. It may even work on a different kind of cancer. Clinical trials are needed to study these possibilities.
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