LYCOS RETRIEVER 
Merck: Merck Serono
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ZymoGenetics and Merck Serono are developing atacicept as a potential treatment for autoimmune diseases and B-cell malignancies. Merck Serono is the study sponsor... ZymoGenetics will operationally conduct the lupus nephritis study. The companies plan to conduct a second study in patients with general systemic lupus erythematosus, for which the SPA review process is ongoing.
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"Developing a novel, effective, oral therapeutic for cancer patients is the primary goal of our Aurora kinase collaboration with Merck Serono," said Rigel's chief operating officer, Raul Rodriguez. "We are proud that Merck Serono has re-affirmed its commitment to this program."
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Safinamide, an alpha-aminoamide derivative that is orally administered, is currently being developed by Merck Serono and Newron as an add-on treatment for patients with Parkinson's disease. Safinamide is believed to have a novel dual mechanism of action based on the enhancement of the dopaminergic function (through potent, reversible inhibition of monoamine oxidase-B [MAO-B], and dopamine uptake) and reduction of glutamatergic activity by inhibiting glutamate release.
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