LYCOS RETRIEVER 
Laser: Tissue
built 629 days ago
In 1981, Rangaswamy Srinivasan discovered that an ultraviolet excimer laser could etch living tissue in a precise manner with no thermal damage to the surrounding area. He named the phenomenon Ablative Photodecomposition (APD). Srinivasan and his co-inventors ran tests using the excimer laser and a conventional, green laser to etch organic matter. They discovered that while the green laser produced rough incisions, damaged by charring from the heat, the excimer laser produced clean, neat incisions. In 1983, Srinivasan collaborated with an ophthalmic surgeon to develop APD to etch the cornea[1].
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The significance of the condition of the tissue can clearly be seen in an experiment by Steinlechner [E28] in which keratinocytes, present in 1% and 5% solutions of fetal calf serum, were irradiated with laser light. The cells in the less nutritious solution were stimulated most. The same observation has been made by Yamamoto [E36], irradiating human fibroblasts. There is reason to beleive that the outcome of many in vitro studies has been just as influenced by the nutrient conditions of the cells as by the laser parameters.
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The second step of the procedure is to use an excimer laser (193nm) to remodel the corneal stroma. The laser vaporizes tissue in a finely controlled manner without damaging adjacent stroma by releasing the molecular bonds that hold the cells together. No burning with heat or actual cutting is required to ablate the tissue. The layers of tissue removed are tens of micrometers thick.
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Waterlase, "For ten years of watching lasers in dentistry, we have waited for an effective hard and soft tissue laser. The wait is over, the Waterlase is an important milestone for dentistry. Congratulations to BIOLASE!"
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The product, which was launched in early 2007, uses a 1064 nm Nd:YAG laser to deliver energy directly to subcutaneous fat cells, causing them to rupture. The emitted fat-melting energy ... coagulates tissue, thus inducing collagen retraction and tissue tightening.
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