LYCOS RETRIEVER 
Lamivudine: Zidovudine
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Lamivudine comes in liquid and tablet form and is taken by mouth. Lamivudine is ... available combined with the NRTI zidovudine (in a tablet called Combivir), with the NRTI abacavir sulfate (in a tablet called Epzicom), and with the NRTIs abacavir sulfate and zidovudine (in a tablet called Trizivir). Lamivudine also comes in lower dose liquid and tablet forms (called Epivir-HBV) for the treatment of hepatitis B virus (HBV) infection. The lower dose form of lamivudine is for individuals who have HBV infection only. Patients who have both HBV and HIV infection should not use this lower dose.
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A Phase II/III 48-Week, Randomized, Double-Blind, Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Lamivudine 300mg QD vs Lamivudine 150mg BID in Combination with Zidovudine 300mg BID and Efavirenz 600mg QD in Antiretroviral-Naïve Adults with HIV-1 Infection. 48-Week Report
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Lamivudine and zidovudine can lower the blood cells in your body that help you fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. To be sure your blood cells do not get too low, your blood will need to be tested on a regular basis. It is important that you not miss any scheduled visits to your doctor.
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Lamivudine exposure was increased by 44% and lamivudine renal clearance was decreased by 30% when coadministered with sulfamethoxazole/trimethoprim. Concurrent administration of lamivudine and zidovudine in one small study resulted in a 39% increase in peak plasma concentration of zidovudine with no significant changes in the area under the concentration-time curve (AUC) or total clearance of lamivudine or zidovudine.[31]
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When it is to be taken :Lamivudine may be used prophylactically in health care workers at risk of acquiring HIV infection after occupational exposure to the virus. In combination with zidovudine for treatment of HIV infection.
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Zidovudine