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Kawasaki Disease: United States
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By far, the highest incidence of Kawasaki disease occurs in Japan (175 per 100,000), though its incidence in the United States is increasing. Kawasaki disease is predominantly a disease of young children, with 80% of patients younger than 5 years of age. Additional risk factors in the United States include Asian race and male sex.
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Kawasaki’s disease is most prevalent in Japan with an annual incidence of about 112 cases per 100,00 children less than 5 years old. In the United States more than 4,000 children are hospitalized with Kawasaki’s disease annually, with a median age of 2 years and a predominance in Americans of Asian and Pacific Island descent. The incidence of Kawasaki’s disease in the United States is intermediate in Hispanics and African Americans and lowest in white children. When Kawasaki’s disease appears in older children, cardiac complications are more likely to occur and may be related to a late diagnosis.
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Kawasaki disease, the leading cause of acquired heart disease in children in the United States, is characterized by inflammation of blood vessels throughout the body, especially the coronary arteries around the heart. The disease is most common in children under 5 years of age, occurs more often in boys than in girls, and is more prevalent during the winter and spring months.
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Kawasaki disease is not a rare illness, with about 3,500 reported cases per year in the United States and over 8,000 per year in Japan. The disease occurs most commonly among children of Asian ancestry, but it affects children of all racial and ethnic groups.
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Kawasaki disease occurs most frequently in Japan and Korea and in individuals of Japanese and Korean ancestry, but it can be found among all racial groups and on every continent. In the United States alone, more than three thousand cases are reported each year, typically among older infants and preschoolers.
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Kawasaki disease occurs in 19 out of every 100,000 kids in the United States. It is most common among children of Japanese and Korean descent, but the illness can affect all ethnic groups.
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