LYCOS RETRIEVER
Kawasaki Disease: Ages
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The medical management of Kawasaki disease (KD) involves the use of gamma globulin and aspirin as anti-inflammatory agents and long-term anticoagulation. Some controversy exists about the ideal timing to begin gamma-globulin, but that is not an issue that concerns emergency physicians.
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The causative agent of Kawasaki disease is still unknown. However, current etiological theories center primarily on immunological causes for the disease. Much research is being performed to discover a definitive toxin or antigenic substance, possibly a superantigen, that is the specific cause of the disease. An unknown virus may play a role as an inciting factor as well.
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The causative agent of Kawasaki disease remains to be unknown. However, an immune- mediated mechanism and an unidentified virus has been presently hypothesized as possible causative factors. Therefore, continuous research is being done to eventually discover a definitive toxin or antigenic substance that is specifically causing the disease.
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The causative agent of Kawasaki disease is still unknown. But current etiologicaltheoriescenter on immunologicalcauses for the disease. Much research is being performed to discover a definitive toxinor antigenicsubstance, possibly a superantigen, that is the specific cause of the disease.
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Epidemiologic features and clinical presentation suggest an infectious etiology for Kawasaki disease. To date... an etiologic agent has not been documented. A variety of infectious agents have been proposed, including rickettsiae, viruses (primarily Epstein-Barr virus and retroviruses), Streptococcus viridans, staphylococci, Propionibacterium species and parvovirus. Standard laboratory studies have been unsuccessful in identifying a specific agent.19
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