LYCOS RETRIEVER 
Intermolecular Force
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Intermolecular Forces Intermolecular forces are those forces that are exerted on one molecule of a substance by those of another and if sufficiently strong may result in the substance being a liquid or a solid. If the natural kinetic energy of a molecule at a particular temperature is greater than the energy resulting from intermolecular forces then the substance will be a vapor or gas at that temperature. There are three basic types of intermolecular forces, those due to transient, random charges, spontaneously generated continuously all over the molecule which are called dispersion forces (originally called London�s Dispersion forces), those due to permanent dipole or induced dipole interactions which are called polar interactions and those due to interactions between permanent charges on the molecules which are called ionic interactions. Dispersive interactions are the only type of interaction that can exist to the exclusion of all others. Polar interactions are always accompanied by dispersive interactions and ionic interactions are always accompanied by dispersive interactions and usually ... by polar interactions. Hydrophobic interactions are the same as dispersive interactions but the term is normally used to describe the overall interactive character of a molecule.
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The Intermolecular Forces (forces between molecules) are weaker than Intramolecular Forces (The Chemical Bonds within an Individual Molecule). This distinction is in fact what leads to the definition of the molecular unit itself.
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A force field [14] is a set of mathematical functions designed to reproduce intermolecular interaction energies, and intramolecular conformational energies, as accurately as possible without the need to carry out new quantum mechanical calculations on each system studied. Using this kind of approach reduces the problems associated with the size and conformational flexibility of protein-ligand complexes.
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Force Field Evaluation Suite: a collection of programs designed for assessing the performance of molecular force fields for conformational energies and intermolecular interactions. The package can ... be used to test the accuracy of force-field optimized molecular geometries. Online download is available, as are numerous sample inputs.
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Intermolecular forces exist in three different levels of strength. The differing strengths are a function of the magnitude of the areas of charge that hold them together. These three different forces are
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London forces the weakest type of intermolecular attraction; can be thought due to motion of electrons leading to temporary dipoles. These temporary dipoles, in turn, induce opposite temporary dipoles in adjacent molecules... causing weak electrostatic attraction.
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Intermolecular Force