LYCOS RETRIEVER 
Infections: Invasive Fungal Infections
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Invasive fungal infections most often occur in people who are immunocompromised or immunosuppressed, and are increasingly caused by moulds such as Aspergillus. IFIs are a leading cause of death in these high-risk populations. Patients undergoing hematopoietic stem cell transplant or chemotherapy for hematological malignancies such as acute myelogenous leukemia (AML) or myelodysplastic syndromes (MDS) who develop IFIs have a high mortality rate of 60-90 percent.(1)
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NEW YORK, Jan. 24 // -- Each year more than 1.3 million hospital patients are affected by Invasive Fungal Infections (IFIs). Once these infections are established in high-risk patients, such as stem cell transplant recipients or chemotherapy patients, they are extremely difficult to treat and are often fatal.
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"I am pleased that the CHMP has granted a positive opinion for posaconazole in refractory invasive fungal infections. This will offer the medical community in Europe an oral therapy for severely ill patients who are struggling not only with their hematological malignancies but ... with difficult fungal infections requiring long-term treatment," said Raoul Herbrecht, MD, professor and head of hematology in the Department of Hematology and Oncology, University Hospital of Strasbourg, France.
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Invasive Fungal Infections