LYCOS RETRIEVER 
Imitrex: Pain
built 622 days ago
Imitrex was well-tolerated. Adverse events were reported in association with 26% of attacks in which placebo was given compared with 35% of attacks in which Imitrex was administered. Adverse events mainly consisted of injection site reactions (e.g., pain, swelling, erythema) dizziness, tiredness, paresthesias and hot and cold sensations.
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Imitrex can cause serious side effects on the heart, including heart attack or stroke. Although these side effects are rare, do not use this medication if you have a history of heart disease, angina (chest pain), blood circulation problems, ischemic bowel disease, severe or uncontrolled high blood pressure, or history of a heart attack or stroke.
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Thirty-four patients with a history of cluster headache (as defined by IHS criteria) administered Imitrex 6 mg SC via an auto-injector within 10 minutes after the onset of attacks (8-49 attacks treated per person). Patients were instructed to record the time lag before the pain started to cease, the time period elapsing thereafter for the pain to disappear, and the time that the accompanying autonomic symptoms (nasal congestion, rhinorrhea, lacrimation, conjunctival injection, miosis/ptosis, and swelling of eyelids) and photophobia remained after the pain had ended. Pain was completely and rapidly (beginning within 4-14 minutes) relieved in all patients. Several accompanying autonomic symptoms (nasal congestion, rhinorrhea, lacrimation, and swelling of eyelids) disappeared in parallel with the relief of pain.
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