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Hydrochlorothiazide
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Pregnancy, breast-feeding Hydrochlorothiazide crosses the placental barrier and appears in umbilical cord blood. The hazards include fetal or neonatal jaundice, thrombocytopenia, and possible other adverse reactions which may have occurred in the adult. It appears in breast milk (Reynolds, 1989; Barnhart, 1987).
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If hyperkalemia is present, Hydrochlorothiazide/triamterine should be discontinued immediately and a thiazide alone should be substituted. If the serum potassium exceeds 6.5 mEq/liter more vigorous therapy is required. The clinical situation dictates the procedures to be employed. These include the intravenous administration of calcium chloride solution, sodium bicarbonate solution and/or the oral or parenteral administration of glucose with a rapid-acting insulin preparation. Cationic exchange resins such as sodium polystyrene sulfonate may be orally or rectally administered. Persistent hyperkalemia may require dialysis.
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Hydrochlorothiazide and lisinopril is available with a prescription under the brand names Prinzide and Zestoretic. Other brand or generic formulations may ... be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.
U.S. National Institutes of Health A Comparison of Telmisartan 80 mg + Hydrochlorothiazide 12.5 mg With Amlodipine 10 mg + Hydrochlorothiazide 12.5 mg in the Control of Blood Pressure in Older Patients With Predominantly Systolic Hypertension. A Prospective, Randomised, Open-Label, Blinded End-Point Evaluation. (ATHOS Study)
Hydrochlorothiazide can make your skin more sensitive to sun or ultraviolet light. Keep out of the sun, or wear protective clothing outdoors and use a sunscreen (at least SPF 15). Do not use sun lamps or sun tanning beds or booths.
Hydrochlorothiazide may cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness.
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