LYCOS RETRIEVER 
Human Growth Hormone: Pituitary Gland
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Blood measurements of insulin-like growth factor 1 (IGF-1), a protein that reflects growth hormone activity, may be used as a screening or diagnostic test. In addition, imaging studies (with CT or MRI) are typically performed to make sure that there are no structural abnormalities involving the pituitary gland.
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South Florida "anti-aging" clinics have been selling human growth hormones, or HGH, since the 1990s. The owners grasped onto a few small studies suggesting that symptoms of aging declined after shots of HGH, which is made by the pituitary gland to control metabolism.
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Estrogen/progesterone replacement (for women) or testosterone replacement (for men) may ... add to the benefits from hormone replacement therapy. These hormones all decline with age. The goal of hormone replacement therapy is to restore levels to those normally present during early adulthood. Safe levels produced by the pituitary gland at age 30 will remain safe when replaced to that same level later in life.
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According to Dr. Judith Reichman, growth hormone is usually produced in the pituitary gland. When released, it causes the production of insulin like growth factors by the liver, that go on to act the tissues and bones.
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HGH is secreted into the blood by the somatotrope cells of the anterior pituitary gland, in larger amounts than any other pituitary hormone. The transcription factor PIT-1 stimulates both the development of these cells and their production of HGH. Failure of development of these cells, as well as destruction of the anterior pituitary gland, results in HGH deficiency.
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Somatostatin is a hormone that blocks the release of HGH by the pituitary gland. The natural production of somatostatin increases with age, and causes a corresponding decrease in HGH production by the pituitary gland.
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Pituitary Gland