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Human Genome Project: Science
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The $1 million, two-month project is a collaboration of 454 Life Sciences and the BCM Human Genome Sequencing Center, said Dr. Richard Gibbs, director of the HGSC and a scientific advisor to the Connecticut-based company. The announcement, aside from its meaning to Watson, is significant because it demonstrates that it will be possible in the future to sequence anyone’s genome – a goal toward which many sequencing firms are working. The time and cost will decrease as the technology improves.
During 1995, HGS and TIGR signed a deal with Takeda Chemical Industries, Ltd. (Chuo-ku, Osaka, Japan) to develop and commercialize human genome products in Japan ("Human Genome Sciences", 1999). The number of alliances increased during the following year when HGS and SmithKline enlarged the scope of their agreement to include Schering Plough Corp. (Madison, NJ), Synthnélabo (now: Sanofi-Synthélabo; Paris, France), and Merck KGaA (Darmstadt, Germany) ("Enough to go around", 1996). Despite these successes, the business relationship between HGS and TIGR grew increasingly distant, and in June 1997, HGS and TIGR announced the end of their partnership (Wickelgren, 1999).
Sequence and analysis of the human genome working draft was published in February 2001 and April 2003 issues of Nature and Science. See an index of these papers and learn more about the insights gained from them.
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Success of the HGP critically depends on bioinformatics and computational biology as well as training of scientists to be skilled in the genome sciences. The project must continue a strong commitment to support of these areas.
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The human genome project, a project so advanced that it sounds straight out of a science fiction novel. Begun in 1990, the project was completed two years ahead of schedule in 2003.
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