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Herpes: Hsv-1
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There are several tests for herpes. If signs and symptoms are present, a health care provider can look at the area, take a sample (culture) from the symptomatic area, and test to see if the herpes virus is present. From this culture test, a second test can be run to tell whether the virus present is HSV-1 or HSV-2. A culture test will not work if the lesions have healed, and might not work if they're more than a few days old.
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Human herpes viruses all share some common properties. The structure of herpes viruses consists of a relatively large double-stranded, linear DNA genomes encased within an icosahedral protein cage called the capsid, which is wrapped in a lipid bilayer membrane called the envelope. This complete particle is known as the virion.[5] The number of genes (called open-reading frames, ORFs) encoding proteins identified in the genomes of both HSV-1 and HSV-2 is 74.[6]
Either of two viruses can cause herpes: herpes simplex type 1 (HSV-1) and herpes simplex type 2 (HSV-2). Both are part of a larger family of "herpesviruses" that includes varicella zoster virus, the cause of chicken pox and shingles; and Epstein Barr virus, the cause of "mono."
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Everyone is at risk for oral herpes from HSV-1, including children many of whom are already infected by age three. In fact, studies suggest that by adolescence 62% of Americans are infected with HSV-1 and by the time one is in the 40's, 90% have been infected.
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HSV-1 is responsible for only 5-10% of genital herpes cases, while HSV-2 causes the majority of genital herpes cases. HSV-2 can be transmitted through oral or genital secretions. An estimated 86 million people worldwide are thought to have genital herpes.
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Up to 80% of Americans have had the most commonly found form of herpes (HSV-1) at some time. Herpes simplex virus 1 is normally oral herpes and is not always spread through sexual contact.
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