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Hemophilia: Classic Hemophilia
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Hemophilia is the oldest known hereditary bleeding disorder. There are two types of hemophilia, A (Classic Hemophilia) and B (Christmas Disease). Both are caused by low levels or complete absence of a blood protein essential for clotting. Patients with hemophilia A lack the blood clotting protein, factor VIII (8), and those with hemophilia B lack factor IX (9). There are about 20,000 hemophilia patients in the United States. Each year, about 400 babies are born with this disorder.
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Hemophilia is a rare genetic bleeding disorder that primarily affects males. People with hemophilia do not have enough of, or are missing, one of the blood clotting proteins normally found in blood. Two of the most common forms of hemophilia are A and B. In people with hemophilia A (... called classic hemophilia), clotting factor VIII is deficient or absent. In people with hemophilia B (also called Christmas disease), clotting factor IX is deficient or absent. People with hemophilia do not bleed more profusely or bleed faster than normal; they bleed for a longer period of time. In most cases, there is a family history (it is a hereditary disorder), but in as many as 30% of cases, there is no family history of hemophilia.
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Hemophilia caused by a defect in or a lack of clotting factor VIII is called hemophilia A (sometimes known as classic hemophilia). Hemophilia caused by a defect in or a lack of clotting factor IX is called hemophilia B (sometimes known as Christmas disease, named for the first person who was known to have this disorder).
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Hemophilia is an inherited bleeding disorder characterized by prolonged or spontaneous bleeding, especially into the muscles, joints, or internal organs. About 17,000 Americans have hemophilia. The disease is caused by deficient or defective blood coagulation proteins known as factor VIII or IX. The most common form of the disease is hemophilia A, or classic hemophilia, in which the clotting factor VIII is either deficient or defective. Hemophilia B is characterized by deficient or defective factor IX.
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Hemophilia A is the most common form of hemophilia, occurring in about 90% of all cases of hemophilia. People with hemophilia A... called "classic hemophilia," have a deficiency in clotting factor VIII. The clotting factor is either missing or present at a low level.3
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Classic Hemophilia