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Hemophilia: Blood
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Hemophilia A is a rare, inherited blood-clotting disorder. People with hemophilia A are deficient in a key protein -- factor VIII -- which is vital in the clotting mechanism to prevent bleeding. Hemophilia A can be characterized by spontaneous hemorrhages or prolonged bleeding, typically into joints and soft tissue. Most patients with hemophilia A are dependent on factor VIII replacement therapy.
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Hemophilia is an inherited bleeding, or coagulation, disorder. Persons with hemophilia lack the ability to stop bleeding because of the low levels, or complete absence, of specific proteins, called "factors," in their blood that are necessary for clotting. Proper clotting of blood helps prevent excessive bleeding. There are several types of hemophilias, but the most common and well known include the following:
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Hemophilia is a rare genetic bleeding disorder that almost always occurs in males. A person has hemophilia when he or she inherits problems with certain blood-clotting factors, making them unable to work properly. Blood-clotting factors are needed to help stop bleeding after a cut or injury and to prevent spontaneous bleeding. The hemophilia gene can contain many different errors, leading to different degrees of abnormality in the amount of clotting factor produced.
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Haemophilia A (... spelled Hemophilia A or Hæmophilia A) is a blood clotting disorder caused by a mutation of the factor VIII gene, leading to a deficiency in Factor VIII. It is the most common hemophilia. Inheritance is X-linked recessive; hence, males are affected while females are carriers or very rarely display a mild phenotype. 1 in 5,000 males are affected.
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Hemophilia is a genetic disorder of the blood clotting system. Over 50 substances are needed for blood to clot. If one of the substances is missing or if the amount of the substance is too low, the person may bleed spontaneously or suffer prolonged bleeding following an injury or trauma. Hemophilia occurs almost exclusively in males.
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Hemophilia is an inherited disorder in which the blood does not clot normally because there is a lack of certain clotting factors. There are two main types of hemophilia: hemophilia A (the most common type) and hemophilia B. While hemophilia usually occurs only in males, there are rare exceptions in which a female will have the blood disorder. Symptoms of hemophilia include bleeding (which may occur internally in joints and muscles) and bruising. Treatment for hemophilia most often involves replacement therapy, in which the clotting factor missing in people with the disease is replaced.
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