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Fragile X Syndrome: Mental Retardation
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Fragile X Syndrome: Diagnosis, Treatment, and Research (Johns Hopkins Series in Contemporary Medicine and Public Health) Fragile X syndrome is the most common inherited form of mental retardation. Now substantially revised and updated, this acclaimed book discusses the clinical approach to diagnosing the disorder, supported by the latest research in epidemiology, molecular biology and genetics, and neuropsychology. It ... presents information on treatment: genetic counseling, pharmacotherapy, intervention, and gene therapy.
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This review highlights the physical, intellectual, academic, behavioral, and communication characteristics associated with fragile X syndrome, the most common inherited form of mental retardation. Educationally relevant problems linked to fragile X are noted, including learning disabilities, attention deficit disorders, speech and language deficits, autism, and behavior disorders.
Fragile X syndrome is the second most common chromosomal cause of mental retardation. The severity of cognitive, language and behavioral outcomes may be related to the actual number of CCG amino acid repeats at the affected site on the lower end of the X chromosome.
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