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Fosamax
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Alendronate, or Fosamax® is a compound that can alter the cycle of bone breakdown and formation in your body. Alendronate can ... increase the formation of new bone. Alendronate, or Fosamax® is also used to prevent and treat osteoporosis and to treat Paget's disease. Alendronate, or Fosamax® can also be used to treat osteoporosis that is caused by treatment with a corticosteroid. Fosamax® may also be used for other purposes not listed here. Alendronate, or Fosamax® is also combined with vitamin D, and marketed under the name Fosamax® plus D.
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Fosamax (alendronate), a drug that has been on the market for almost 10 years, has been linked to osteonecrosis of the jaw (ONJ). Otherwise known as "dead jaw", osteonecrosis is a severe condition in which the jaw dies and is unable to regenerate, eventually leading to extreme pain and exposed bone in the mouth. Fosamax is part of a class of drugs known as bisphosphonates, which are used to treat osteoporosis and bone pain caused by some types of cancer. Bisphosphonates are often used in the management of certain cancers—such as lung, breast, prostate, and multiple myeloma—where cancer has metastasized (spread) to the bone. Bisphosphonates are absorbed into the bone tissue where the drug may remain for some period of time. It is believed that the drugs interfere with the deposition and absorption of calcium in the bone possibility leading to the degeneration of the bone tissue, and may apply to both oral and intravenous administration of the drug.
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If you take Fosamax every day and you miss a dose, skip that dose and take the next regularly scheduled dose the following day. Missing one dose will not affect your treatment. Do not take two tablets at the same time. If you take a Fosamax once a week and you miss a dose, take the missed dose on the morning after you remember. Do not take two tablets on the same day. Return to taking one tablet once a week, as originally scheduled on your chosen day.
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For Fosamax to be effective, you must take the tablets without food or other medications, exactly as directed. Fosamax is effective only when each tablet or bottle of oral solution is taken with a full glass of plain water first thing in the morning, at least 30 minutes before the first food, beverage, or other medication. If you can wait longer before eating or drinking, the medication will be absorbed better. Do not lie down after taking Fosamax until at least 30 minutes have passed and you've had something to eat.
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Fosamax drugs have been linked to the catastrophic “DEAD JAW” (Osteonecrosis of the jaw) disease. Fosamax is a drug, within a class of drugs, known as bisphosphonates. Bisphosphonates are effective in the prevention of bone resorption (the process of resorbing), and ... inhibit bone density loss. Bone resorption plays a critical role in maintaining normal bone homeostasis, in fighting infection, and in the healing process. Jaw problems can begin from such small dental procedures such as filings, root canals, etc. while taking Fosamax.
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Fosamax is effective only when each tablet is taken with a full glass of plain water first thing in the morning, at least 30 minutes before the first food, beverage, or other medication. If you can wait longer before eating or drinking, the medication will be absorbed better. Do not lie down for at least 30 minutes after taking Fosamax and avoid chewing or sucking on the tablet; it can cause mouth sores. You should take calcium and vitamin D supplements if you don't get enough in your diet. Avoid smoking and alcohol. Weight-bearing exercise can ... strengthen bones.
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Fosamax