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Foradil: Drugs
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This list is not complete and there may be other drugs that can interact with Foradil. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
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An FDA advisory panel announced that Novartis AG’s Foradil asthma drug, marketed by Schering-Plough Corp., should have a warning about the risk for worsened breathing similar to that on GlaxoSmithKline Plc’s Advair and Serevent. The drug shares the ingredient salmeterol with London-based Glaxo’s Advair and Serevent. All three medicines work by easing constriction within the lung. The FDA panel ... voted to say Serevent, Advair and Foradil are safe enough to remain on the U.S. market.
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The drugs are Advair and Serevent, made by GlaxoSmithKline, and Foradil, made by Novartis and sold in the United States by Schering Plough. Advair and Serevent contain the same drug, salmeterol; in Serevent, salmeterol is alone, while in Advair it is combined with another medicine. Foradil does not contain salmeterol; its active ingredient is formoterol.
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The user-friendly Aerolizer Inhaler accurately dispenses a precise dose of Foradil that patients can "hear, feel and see." In the past, patients and parents of children with asthma have been concerned about confirming that a correct dose of asthma medication has been delivered. The Aerolizer Inhaler can be visually inspected, and the inhaler makes a whirring noise, signaling that the drug is being dispensed.
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The committee voted 12 to zero, with one abstention, that labeling for Foradil (formoterol) should include a warning citing asthma-related deaths seen with Serevent (Salmeterol). Labeling for Serevent, and combination product Advair (Salmeterol/Fluticasone), was modified in September 2004 to incorporate statistics from the SMART study. The study illustrated a 1.71 relative risk of asthma death or life-threatening experience with use of Salmeterol compared to placebo. The drugs added a boxed warning in August 2003 based on the preliminary results of the study.
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