LYCOS RETRIEVER 
Folic Acid: Blood
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Folic acid might prevent nitroglycerin-induced nitrate tolerance and cross tolerance to endothelial nitric oxide, which plays a role in blood pressure control. These conditions need to be treated by a qualified healthcare provider.
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Taking folic acid in tandem with vitamin B12 may be beneficial if you have anemia caused by a deficiency of either one of these vitamins. Together they work to boost the production of red blood cells. Be sure to always take the two vitamins together, and under a doctor's supervision, because a high intake of one can mask a deficiency of the other. Vitamin B12 deficiency can cause irreversible nerve damage and dementia.
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Controlling homocysteine can be achieved by supplementing with 4 common nutrients: vitamins B6, B12, folic acid and betaine. Vitamins B6, B12, and folic acid blood levels are found to be inversely related to plasma homocysteine concentration. Combination therapy with the aforementioned vitamins provides an effective way to reduce homocysteine levels,11 and side effects of this therapy are relatively unknown.12 Another supplement that has demonstrated usefulness in lowering homocysteine levels is betaine... known as trimethylglycine.
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People with certain conditions, such as kidney failure and some types of cancer, may use up folic acid quickly. They may need their blood to be cleaned using a machine (kidney dialysis).
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