LYCOS RETRIEVER 
Fluoride: Concentrations
built 629 days ago
Given the relatively low concentration of fluoride in ACT® Fluoride Rinse and Restoring™ Mouthwash , and the fact that it is not ingested, conditions associated with over-fluoridation such as fluorosis are not considered to be an issue. Please consult with your physician or dental professional about any health concerns you may have, as your physician is familiar with you and your personal medical history.
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A 2000 article in the journal Fluoride describes the bone effects of fluoride in detail.(105) Fluoride may increase bone quantity (osteofluorosis, osteosclerosis) but ... decrease bone quality and bone strength. It is well known that pharmacological doses of fluoride increase the risk of torsion-type fractures (such as hip fractures) despite the appearance of greater bone density. Conventional medicine interprets the observed fluoride-induced increase of serum alkaline phosphatase concentration as a sign of osteoblast activity. Actually, it is a reflection of increased mortality of osteocytes within bone. Osteocytes are rich in alkaline phosphatase, which is released when the cells are killed by fluoride. It is unlikely, therefore, that a window of fluoride-induced bone benefit exists.(106)
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Fluoride uptake in vitro and in vivo, reaction, and release in the enamel are strongly dependent on the duration of contact with the fluoride agent. Fluoride varnishes may be optimal in that respect. The cariostatic action of topical fluoride is most likely a combination of various mechanisms. The availability of fluoride in the liquid phase around the apatite crystallites is today believed to be more important in decreasing dissolution of crystallites than fluoride incorporation in the crystal lattice. In fact, very low liquid fluoride concentrations (in the ppm range) under low pH-conditions can block crystalline dissolution almost completely and/or reduce the rate of demineralization (Arends and Christoffersen, J Dent Res 1986; 65: 2-11; ten Cate, J Dent Res 1990; 69: Spec issue: 614-619).
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Fluoride concentrations in most private drinking water wells in Loudoun County are so low that they cannot be detected. However, fluoride concentrations in a few water wells have been above two milligrams per liter and, in very few wells, have shown a fluoride concentration of greater than four milligrams per liter.
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