LYCOS RETRIEVER 
Fibroids: Submucosal Fibroids
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Fibroids may be single or multiple. Most fibroids start in an intramural location,- that is the layer of the muscle of the uterus. With further growth, some lesions may develop towards the outside of the uterus (subserosal or pedunculated), some towards the cavity (submucosal or intracavitary). Lesions affecting the cavity tend to bleed more and interfere with pregnancy. Secondary changes that may develop within fibroids are hemorrhage, necrosis, calcification, and cystic changes. Less frequently, leiomyomas may occur at the lower uterine segment, cervix, or uterine ligaments.
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Fibroids can grow in different parts of the uterus. Pedunculated fibroids are attached to the uterine wall by stalks. Subserosal fibroids extend outward from the uterine wall. Submucosal fibroids expand from the uterine wall into the uterine cavity. Intramural fibroids develop within the uterine wall. Different types of fibroids are associated with different symptoms.
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Fibroids... called leiomyomas or fibromas, are benign (non-cancerous) uterine tumors. They are made up of normal uterine muscle cells, growing in abnormal, disorganized clumps. A good comparison is moles on the skin–also normal tissue in abnormal clumps. Fibroids can grow within the uterine wall ("mural" type), on the outside of the uterus ("serosal" type), or inside the uterine cavity ("submucosal" type). They can even grow on a mushroom–like stalk ("Pedunculated" type).
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Submucosal Fibroids - As the least common of uterine fibroids, submucosal fibroids grow beneath the uterine cavity lining. This type of fibroid will typically show symptoms in the form of abnormal uterine bleeding in terms of menstrual flow and duration.
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A recently published study from Monash University in Australia compared the pregnancy rates following IVF treatment for women known to have fibroids at the time of treatment with those for women without fiboids. There was no difference in the pregnancy rates when the fibroids were pedunculated or subserosal, but when they were intramural or submucosal the pregnancy rates were up to 50% less than for normal women. This report is beginning to influence more doctors to treat fibroids prior to fertility treatments.
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Occasionally, fibroids can have a negative impact on fertility. Approximately 3% of women with uterine fibroids find that they have trouble conceiving because of these growths. The impact of fibroids on your fertility depends upon the size and location of your fibroids. Subserosal and intramural fibroids are usually unrelated to fertility issues. However, submucosal fibroids can sometimes interfere with fertilization and implantation.
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Submucosal Fibroids